Pressurised Metered-Dose Inhaler (pMDi)Valve Investigation and Testing Programme

Background

A Kestrel client was engaged by a major European pharma customer to evaluate the use of less environmentally damaging pressured Meter Dose Inhaler  (pMDI) propellant gasses in existing canister designs.

The investigation included testing of existing canister valve designs and an assessment of an accelerated leak testing programme using low molecular weight gas.

Kestrel’s role was initially to provide technical input and review of existing canister designs, performance and root cause analysis of leak rates in samples. Following staff resignations, illness and disruption during the COVID-19 pandemic, Kestrel stepped in to take over control of the project.

Requirement

Provision of external replacement resource to continue test and analysis work following resignations

Overall project management and delivery to shifting client timescales amid disruption due to COVID-19

Response

An external test team was engaged, contracts agreed, and plans drawn up to continue the project under COVID-19 Lockdown restrictions.

The project was replanned, re-costed and re-proposed with the client to meet key milestones. Flexible collaborative working practices were extensively used to ensure continuation of work, manage project risk and ensure clear communication to keep clients engaged and informed.

Result

All samples were tested, analysed and results tabulated and communicated with client on time and on budget. Successful result led to further requests for multiple follow-on projects.